In recent years, research has increasingly turned to natural substances that have the potential to positively impact our health. One such substance that has garnered attention is nattokinase. Originally derived from natto, a traditional Japanese food produced by fermenting soybeans with the bacterium Bacillus subtilis, nattokinase has gained popularity due to its unique properties and potential health benefits. One of the areas of research that has garnered interest in recent years is the effect of nattokinase on the thyroid. This article will explore the properties of nattokinase, its potential effects on thyroid function, and the scientific evidence surrounding this topic.
What is nattokinase?
Nattokinase is an enzyme extracted from natto. It has fibrinolytic properties, meaning it can help dissolve fibrin, a protein involved in blood clotting. Because of this property, nattokinase is often associated with improving blood circulation and preventing cardiovascular disease. In addition to these effects, there is also debate about the potential effects of nattokinase on other aspects of human health, including thyroid function.
The thyroid and its importance
The thyroid is a small, butterfly-shaped organ located in the front of the neck that plays a central role in the endocrine system. It produces hormones that regulate metabolism, growth, and development. Dysfunction of the thyroid can lead to various health problems, including hypothyroidism (underactive thyroid), hyperthyroidism (overactive thyroid), and thyroid nodules.
Potential effects of nattokinase on the thyroid
Research on the effects of nattokinase on the thyroid is still in its early stages. Some studies suggest that nattokinase may indirectly have a positive effect on thyroid function through its ability to improve blood circulation and reduce inflammation. Good blood circulation is essential for optimal thyroid function, as it supports the distribution of thyroid hormones throughout the body.
Scientific evidence
To date, there are few direct studies examining the effects of nattokinase on thyroid function. Some preliminary research in animal models and in vitro (test-tube) studies has shown that nattokinase has anti-inflammatory properties and can improve blood circulation, which could theoretically support thyroid function. However, large-scale clinical trials in humans are needed to confirm these potential effects and understand exactly how nattokinase affects the thyroid.
Safety and dosage
Although nattokinase is generally considered safe when consumed in amounts found in food, caution should be exercised when used in supplement form. People taking blood thinners or suffering from blood clotting disorders should especially consult their doctor before taking nattokinase. There are no consistent guidelines yet regarding the optimal dosage of nattokinase for specific health conditions, including those affecting the thyroid. Dosages in studies vary, so it's important to follow the manufacturer's instructions and seek medical advice when taking nattokinase supplements.
Possible side effects and interactions
Side effects of nattokinase are generally rare and mild, but may include stomach upset, nausea, and skin rashes. Due to its blood-thinning effects, there is a potential risk of bleeding, especially when combined with other blood-thinning medications such as warfarin or aspirin. It is also important to consider the potential interaction of nattokinase with medications that affect blood clotting, as well as medications that affect the thyroid, as this could increase or decrease the effects of these medications.
Summary and outlook
Nattokinase is a promising enzyme with potential health benefits, including possible support for thyroid function. Despite the positive signs, scientific evidence regarding the direct effects of nattokinase on the thyroid is still limited. Future research, particularly well-designed human clinical trials, is crucial to clarify the safety, efficacy, and mechanism of action of nattokinase on the thyroid.
The potential health benefits of nattokinase, including its effects on the thyroid, make it an interesting subject for future scientific investigation. However, it is important to exercise caution and seek professional medical advice when using nattokinase as a dietary supplement, especially for individuals with existing health conditions or those already taking medication. Balancing the promising health benefits with safety is essential to fully realize the potential benefits of nattokinase without incurring unwanted risks.More information:
https://www.mdpi.com/2218-273X/12/7/980
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11133624/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11133624/#SM1